A New Reaction of Isatin, Cyclic 1,3-Diketone, and 2-Cyanoacetamide: A Four-Component Synthesis of Spirooxindoles

作者:Ghahremanzadeh Ramin; Hosseini Ghaffar; Akbarzadeh Roya; Bazgir Ayoob*
来源:Journal of Heterocyclic Chemistry, 2013, 50(2): 272-280.
DOI:10.1002/jhet.1010

摘要

A novel reaction of isatins, 2-cyanoacetamide, and cyclic 1,3-diketones in ethanol was reported. The reaction gave the unexpected spirooxindole ethyl carboxylates in excellent yields and the spirooxindole carboxamide was not observed.

  • 出版日期2013-3

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