Acanthamoeba keratitis due to genotype T11 in a rigid gas permeable contact lens wearer in Spain

作者：Lorenzo Morales Jacob; Morcillo Laiz Rafael; Ma Martin Navarro Carmen; Lopez Velez Rogelio; Lopez Arencibia Atteneri; Arnalich Montiel Francisco; Maciver Sutherland K; Valladares Basilio^*; Martinez Carretero Enrique

来源：Contact Lens and Anterior Eye, 2011, 34(2): 83-86.

DOI：10.1016/j.clae.2010.10.007

• Acanthamoeba
• Keratitis
• Spain
• T11

A case of a 59-year-old Spanish patient who presented with severe ocular pain, blurred vision, eyelid swelling and foreign body sensation in the right eye is reported. She was a regular soft contact lens wearer who initially claimed to maintain standard lens care. After exploration, conjunctival injection, dendritiform corneal ulcers and stromal edema were observed. She was initially treated for a possible viral keratitis due to herpes simplex virus using 3% topical acyclovir and 0.1% dexamethasone eye drops 5 times a day. The patient did not respond to this treatment and six weeks later, corneal scrapings were positive for Acanthamoeba genotype T11. She was then treated with chlorhexidine 0.02%, propamidine 0.1% and 1% cycloplegic eye drops hourly which resulted in a significant improvement. After a month, ocular pain decreased and the clinical signs of keratitis ameliorated observed as a diminution of the size of the ulcer and also in the extension and opacity of the corneal infiltrates. The patient has been following this treatment for 3 months and it is possible that she will have to carry on with it for a whole year. To the best of our knowledge, this is the first case of severe keratitis due to Acanthamoeba genotype T11 in Spain.

• 出版日期2011-4