科研之友
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摘要
An efficient regio and stereoselective synthesis of functionalized E-vinyl ethers are described. The reaction could proceed via addition of primary alcohols and phenols to functionalized N-substituted 2-alkynamides which are produced via Ugi-4CR in the presence of triethylamine at room temperature. The reaction proceeds through sequential Ugi/nucleophilic reaction sequence. High yields, short reaction times, and simple operations are the advantages of this approach.
- 出版日期2014-10
