A bisphosphonate tweezers and clickable PEGylated PAMAM dendrons for the preparation of functional iron oxide nanoparticles displaying renal and hepatobiliary elimination

作者:Ghobril Cynthia; Popa Gabriela; Parat Audrey; Billotey Claire*; Taleb Jacqueline; Bonazza Pauline; Begin Colin Sylvie; Felder Flesch Delphine
来源:Chemical communications, 2013, 49(80): 9158-9160.
DOI:10.1039/c3cc43161d

摘要

The functionalization of superparamagnetic iron oxide nanoparticles (SPION) with PEGylated PAMAM dendrons through a bisphosphonate tweezers yielded 15 and 30 nm dendritic nano-objects stable in physiological media and showing both renal and hepatobiliary elimination.

  • 出版日期2013