B7-H3 in Cancer - Beyond Immune Regulation

作者：Flem Karlsen Karine; Fodstad Oystein; Tan Ming; Nunes Xavier Caroline E^*

来源：Trends in Cancer, 2018, 4(6): 401-404.

DOI：10.1016/j.trecan.2018.03.010

B7-H3, a member of the B7 family of immunoregulatory proteins, is overexpressed in cancer and promotes tumor growth, metastasis, and drug resistance. We discuss here the involvement of B7-H3 in cancer that goes beyond its immune regulatory function, and discuss the potential of B7-H3 as a biomarker and therapeutic target.

• 出版日期2018-6