A facile and regioselective one-pot synthesis of novel pyrazolo[1,5:1,2]pyrrolo[3,4-b]quinoline-2,3-dicarboxylate hybrids via intramolecular Wittig reaction

作者：Largani Tahere Hosseyni; Imanzadeh Gholamhasan^*; Pesyan Nader Noroozi; Sahin Ertan; Shamkhali Amir Nasser; Notash Behrouz

来源：Molecular Diversity, 2018, 22(1): 37-46.

DOI：10.1007/s11030-017-9784-1

• Regioselective
• One-pot synthesis
• Pyrrolo[3,4-b]quinoline
• Wittig reaction
• Pyrazole
• Hybrid molecules

The regioselective syntheses of novel pyrazolo[1,5:1,2]pyrrolo[3,4-b]quinoline-2,3-dicarboxylates (6a-l) from pyrrolo([3,4-b]quinolin-2(3H)-yl)benzamides through an intramolecular Wittig reaction are described. This protocol takes advantages of mild conditions, simple workup and high yield which make this method attractive for the synthesis of these hybrid of pyrazolo[1,5:1,2]pyrrolo[3,4-b]quinolines.

• 出版日期2018-2