Anion-induced ring-opening of fluorescein spirolactam: fluorescent OFF-ON

作者：Wu Jia Sheng; Kim Hyun Jung; Lee Min Hee; Yoon Jun Hee; Lee Joung Hae; Kim Jong Seung^*

来源：Tetrahedron Letters, 2007, 48(18): 3159-3162.

DOI：10.1016/j.tetlet.2007.03.060

N-(2,7-Dichlorofluorescein)lactam-N'-phenylthiourea (L) was developed as a colorimetric and fluorescent chemosensor for anions such as AcO-, F- and H,2PO4-. The addition of AcO- anion to the solution of L in CH3CN results in a distinct fluorescence 'ON' observation as well as color change (from colorless to pink). The H-bonding interaction between AcO- anion and thiourea moiety of L induced the ring-opening of the spirolactam of fluorescein moiety, which gave rise to the dual chromo- and fluorogenic changes.

• 出版日期2007-4-30