Antibacterial Nanoparticle Monolayers Prepared on Chemically Inert Surfaces by Cooperative Electrostatic Adsorption (CELA)

作者:Huda Sabil; Smoukov Stoyan K; Nakanishi Hideyuki; Kowalczyk Bartlomiej; Bishop Kyle; Grzybowski Bartosz A*
来源:ACS Applied Materials & Interfaces, 2010, 2(4): 1206-1210.
DOI:10.1021/am100045v

摘要

Cooperative electrostatic adsorption (CELA) is used to deposit monolayer coatings of silver nanoparticles on relatively chemically inert polymers, polypropylene, and Tygon. Medically relevant components (tubing, vials, syringes) coated by this method exhibit antibacterial properties over weeks to months with the coatings being stable under constant-flow conditions. Antibacterial properties of the coatings are due to a slow release of Ag(+) from the particles. The rate of this release is quantified by the dithiol-precipitation method coupled with inductively coupled plasma optical emission spectrometer (ICP-OES) analysis.