Does Collecting Physiological Data Aid in the Diagnosis of Coronary Artery Disease by Nuclear Perfusion Single Photon Emission Computed Tomography Imaging?

作者：Rees Michael^*; Nedeva Petkova Maya; Hanna Azad; Breeze Julian

来源：Journal of Medical Imaging and Health Informatics, 2015, 5(1): 152-157.

DOI：10.1166/jmihi.2015.1371

• Nuclear Stress Perfusion Index
• 12-Lead ECG Stress Test
• MyoQuant Index
• Cardiac Syndrome X

This study examined whether ECG and physiological findings recorded during the stress component of cardiac 99mTc Sestamibi gated SPECT (single photon emission computed tomography) imaging add to the interpretation of the examination. 311 patients (161 male), mean age 66 years (range 31-89 years) were categorized as having myocardial perfusion either within the normal range expressed as the MyoQuant Index, (MQI <= 1) or abnormal perfusion (MQI > 1). Based on results from the continuous 12 lead ECG examination taken during the stress component of this examination, patients were determined to have either ST depression (ST-pos >= 1 mm) or no T changes (ST-neg) 42% of these patients showed ST depression greater than 1 mm. The results show no overall correlation between ST depression and abnormal perfusion. Examination of left ventricular cavity volumes and ejection fraction at rest and cardiovascular haemodynamics (systolic blood pressure, diastolic blood pressure, heart rate) at rest and during stress were carried out. Analysis of this data showed no significant difference between the groups, except for an effect, (p < .01), on the resting heart rate of patients (ST-pos, 86 bpm. (beats per minute). vs. ST-neg, 79 bpm.) and the maximal heart rate (p < .05) (ST-pos 126 bpm. vs. ST-neg. 119 bpm.). This suggests that-the heart rate of-patients should be recorded in this type of examination. Patients with a positive stress test result, and a completely normal perfusion rating, (MQI < 1) accounted for 9% of the total cohort (n = 29, 6 male).

• 出版日期2015-2