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摘要
A novel method for the synthesis of alpha-bromoacetophenones by the reaction of 1,3-dibromo-5,5-dimethythydantoin with p-toluenesulfonic acid in methanol at 20 similar to 60 degrees C was described. Substituted acetophenones at the para or meta position of aromatic ring gave a-bromoacetophenones in high yield. However reaction of o-nitroacetophenone did not take place under the same condition.
- 出版日期2007-1
- 单位华东师范大学
