Ph2P(BH3)Li: From Ditopicity to Dual Reactivity

作者：Consiglio Gabriella Barozzino; Queval Pierre; Harrison Marchand Anne; Mordini Alessandro; Lohier Jean Francois; Delacroix Olivier; Gaumont Annie Claude^*; Gerard Helene; Maddaluno Jacques; Oulyadi Hassan

来源：Journal of the American Chemical Society, 2011, 133(16): 6472-6480.

DOI：10.1021/ja201760c

A multinuclear NMR study shows that the deprotonation of diphenylphosphine-borane by n-BuLi in THF leads to a disolvated lithium phosphido-borane Ph2P(BH3)Li of which Li+ is connected to the hydrides on the boron and two THF molecules rather than to the phosphorus. This entity behaves as both a phosphination and a reducing agent, depending on the kinetic or thermodynamic control imposed to the reaction medium. Density functional theory computations show that H2P(BH3)Li exhibits a ditopic character (the lithium cation can be in the vicinity of the hydride or of the phosphorus). It explains its dual reactivity (H- or P-addition), both routes going through somewhat similar six-membered transition states with low activation barriers.

• 出版日期2011-4-27