A novel rearrangement reaction of beta-diazo-alpha-ketoacetals

作者：Erhunmwunse Marvis O; Steel Patrick G^*

来源：Tetrahedron Letters, 2009, 50(26): 3568-3570.

DOI：10.1016/j.tetlet.2009.03.025

• Rhodium carbenoid
• Wolff rearrangement
• Ketal
• Lactone
• Ketene

Treatment of pyruvate ketal-derived diazoacetoacetates or vinyldiazoketones with rhodium(II) complexes at elevated temperatures results in an Unusual skeletal rearrangement to afford eight-membered ring lactones.

• 出版日期2009-7-1