A Study on Borna Disease Virus Infection in Domestic Cats in Japan

作者：Someya Azusa; Fukushima Ryoko; Yoshida Michiko; Tanahashi Yasuyuki; Prapeuk Tangmunkhong; Iizuka Reiko; Hirami Hiroshi; Matsuda Atsushi; Takahashi Shunichi; Kurita Goro; Kimura Takashi; Seo Misuzu; Funaba Masayuki; Nishino Yoshii^*

来源：Journal of Veterinary Medical Science, 2014, 76(8): 1157-1160.

DOI：10.1292/jvms.13-0349

• antibody
• Borna disease virus
• epidemiology
• feline
• vertical transmission

Borna disease virus (BDV) infection causes neurological disease in cats. Here, we report BDV infection in 199 hospitalized domestic cats in the Tokyo area. BDV infection was evaluated by detection of plasma antibodies against BDV-p24 or -p40. BDV-specific antibodies were detected in 54 cats (27.1%). Interestingly, the percentage of seropositive cats was not significantly different among the three clinical groups, i.e., healthy (29.8%), neurologically asymptomatic disease (22.2%) and neurological disease (33.3%). The specific antibodies were present even in cats aged below one year. The seropositive ratio was constant, irrespective of age and sampling season. The present study suggests that additional factors are required for onset of Boma disease in naturally infected cats and that BDV is transmitted through vertical routes in cats.

• 出版日期2014-8