Development of a novel electrochemical sensor based on cobalt(II) complex useful in the detection of dopamine in presence of ascorbic acid and uric acid

作者：Nagles Edgar^*; Ibarra Laura; Penagos Llanos Johisner; Hurtado John^*; Garcia Beltran Olimpo

来源：Journal of Electroanalytical Chemistry, 2017, 788: 38-43.

DOI：10.1016/j.jelechem.2017.01.057

• Dopamine
• Human urine
• Cobalt(II) complex
• Strippingvoltammetry

[(Co(bdmpzm)(2)(NCS)(2)] (bdmpzm = bis(3,5-dimethylpyrazol-1-yl)methane) was synthesized and combined with single walled carbon nanotubes (SWCNT) and nafion on a screen printed carbon electrode (SPCE). The electrocatalytic activity of modified electrode (Nafion-SWCNT-[Co(bdmpzm)(2)(NCS)(2)]/SPCE) was evaluated for dopamine (DA) oxidation. Anodic and cathodic peak were seen to 0.42 V.and0.29 V respectively, showed a much more quasi-reversible process, (Delta V 0.128) compared with the electrode without cobalt complex. The detection limit (3 sigma/b) for dopamine was 0.095 pmol L-1 The studies of reproducibility determined as relative standard deviation (RSD) was 2.5%.(n = 5) with four different electrodes. The repeatability were 1.5% (n = 5) The new sensor was used in the quantify DA in human urine with an average recovery between 83.0 and 93.0%.

• 出版日期2017-3-1