Assessing truncal obesity in predicting cardiometabolic risk in children: clinical measures versus dual-energy X-ray absorptiometry

作者：Palmieri Vincent J.; Henshaw Melissa H.; Carter Janet; Chowdhury Shahryar M.^*

来源：Acta Paediatrica, 2018, 107(6): 1065-1069.

DOI：10.1111/apa.14175

• Dyslipidemia
• Insulin resistance
• Obesity
• Truncal fat

Aim: The objectives of this study were to 1) compare the accuracy of waist: hip ratio (WHR) and waist: height ratio (WHtR) by determining their association with reference-standard measures derived from dual-energy X-ray absorptiometry (DXA) and 2) assess the relationship of DXA, WHR and WHtR to measures of dyslipidemia, insulin resistance and inflammation in children.
Methods: Subjects aged four to 21 were prospectively recruited. Truncal obesity by DXA was defined as the trunk fat: height ratio and trunk fat: nontrunk fat ratio. Three hundred and eight subjects were studied, and 246 (80%) were obese.
Results: There was a strong correlation between WHtR and trunk fat: height (r = 0.84, p < 0.01). DXA measures of truncal obesity had stronger correlations with measures of cardiometabolic risk than WHR and WHtR. Upon multivariable regression, only WHtR had independent associations with cholesterol/HDL, HOMA-IR and high-sensitivity c-reactive protein.
Conclusion: WHtR is an accurate measure of truncal obesity. WHtR showed stronger associations with measures of insulin resistance and truncal obesity than WHR.

• 出版日期2018-6