New Ursane Triterpene from the Fruits of Terminalia arjuna

作者:Hossain Rashadul*; Sultana Rajia; Adhikari Aychout; Choudhary Muhammad Iqbal; Ali Yusuff; Zaman Shahed
来源:Natural Product Communications, 2014, 9(3): 371-372.
DOI:10.1177/1934578x1400900323

摘要

A new ursane triterpene, torment (2 alpha,3 beta,19 alpha-trihydroxyurs-12-en) (1), was isolated from the fruits of Terminalia arjuna along with four known ursane and oleane triterpenes. The structures were established on the basis of extensive NMR (1D & 2D) and MS (El & ESI) studies. Tormentic acid (2), 19 alpha-hydroxy asiatic acid (3) and olean-12-en-2 alpha,3 beta-diol (4) were isolated for the first time from this species. Compounds 1 and 2 lacked significant enzyme inhibition, cytotoxicity, immunomodulatory and antiglycation activities.

  • 出版日期2014-3