Antifungal Activity of Denture Soft Lining Material Modified by Silver Nanoparticles-A Pilot Study

作者：Chladek Grzegorz^*; Mertas Anna; Barszczewska Rybarek Izabela; Nalewajek Teresa; Zmudzki Jaroslaw; Krol Wojciech; Lukaszczyk Jan

来源：International Journal of Molecular Sciences, 2011, 12(7): 4735-4744.

DOI：10.3390/ijms12074735

• nanotechnology in dentistry
• silver nanoparticles
• antifungal
• dental materials
• soft liner
• Candida albicans

Soft liner materials in oral cavity environments are easily colonized both by fungi and dental plaque. These factors are the cause of mucosal infections. The microorganism that most frequently colonizes soft liner materials is Candida albicans. Colonization occurs on the surface of materials and within materials. A solution to this problem might involve modification of soft liner materials with silver nanoparticles (AgNPs). In this article, we present results showing the antifungal efficacy of silicone soft lining materials modified with AgNPs. The modification process was conducted by dissolving both material components (base and catalyst) in a colloidal solution of AgNPs and evaporating the solvent. Composites with various AgNP concentrations (10, 20, 40, 80, 120 and 200 ppm) were examined. The in vitro antifungal efficacy (AFE) of composite samples was 16.3% to 52.5%.

• 出版日期2011-7