First trimester screening for Down syndrome: Five years prospective experience

作者：Weingertner A S^*; Trieu N T; Kohler M; Viville B; Levy G; Montaya Y; Kutnahorsky R; Tissier I; Kohler A; Tanghe M; Mager C; Benassi E; Cancelier M; Neuman M; Bouffet N; Hunsinger M C; Hornecker F; Langer B; Nisand I; Favre R

来源：Journal de Gynecologie Obstetrique et Biologie de la Reproduction, 2010, 39(5): 353-361.

DOI：10.1016/j.jgyn.2010.04.007

• First trimester screening
• Down syndrome

First trimester screening for Down syndrome is yet to become the first intention strategy in France. This screening program at 11-14 weeks of gestation using maternal age, fetal nuchal translucency, maternal serum free beta-human chorionic gonadotropin and pregnancy-associated plasma protein-A has already been validated for a long time by many international studies. It seems to improve detection rate and decrease false positive rates. We report here five years prospective experience.

• 出版日期2010-9