A Slow Dance for Microtubule Acetylation

作者:Kull F Jon*; Sloboda Roger D
来源:Cell, 2014, 157(6): 1255-1256.
DOI:10.1016/j.cell.2014.05.021

摘要

Microtubules contribute to diverse cellular processes through balancing dynamic, short-lived and stable, long-lived populations. One way in which long-lived microtubules are marked is by post-translational acetylation of alpha-tubulin by tubulin acetyltransferase (TAT). Szyk et al. now provide insight into TAT's mechanism of action and its unique time-stamping ability.

  • 出版日期2014-6-5