Processed Meat Consumption and Squamous Cell Carcinoma of the Oesophagus in a Large Case-Control Study in Uruguay

作者：De Stefani Eduardo^*; Boffetta Paolo; Luis Ronco Alvaro; Deneo Pellegrini Hugo; Correa Pelayo; Acosta Gisele; Mendilaharsu Maria

来源：Asian Pacific Journal of Cancer Prevention, 2014, 15(14): 5829-5833.

DOI：10.7314/APJCP.2014.15.14.5829

• Squamous cell oesophageal cancer
• processed meat
• salted meat
• other cured meats

Background: The role of processed meat in the aetiology of squamous cell oesophageal cancer has been explored in detail. Methods: In the time period 1990-2005, a case-control study was conducted in Montevideo, Uruguay including 2,368 participants (876 cases of oesophageal cancer and 1,492 controls). Relative risks, approximated by the odds ratios, were estimated by multiple unconditional logistic regression. Results: Processed meat was positively associated with oesophageal cancer (upper quartile vs lower quartile OR 2.30, 95% CI 1.72-3.07), whereas salted meat intake was positively associated with squamous cell oesophageal cancer (OR 3.82, 95% CI 2.74-5.33). Finally other cured meats were positively associated with oesophageal cancer (OR 1.65, 95% CI 1.22-2.22). Conclusions: It could be concluded that processed meat consumption could be an important risk factor for the aetiology of squamous cell oesophageal cancer in Uruguay.

• 出版日期2014