摘要
Temporomandibular disorders (TMD) are defined as clinical conditions that involve the masticatory muscles, temporomandibular joint (TMJ) or both. The aim of this study was to evaluate serum 17 beta-oestradiol and progesterone levels in menstruating women affected by internal derangement of the TMJ. A total of 142 women (mean age 30.2 +/- 6.7) who referred to medical diagnostic laboratory of Iranian Academic Centre for Education, Culture and Research (ACECR), Mashhad Branch, were enrolled during 2007 and 2008. Forty-seven individuals had disc displacement with reduction (Group IIa) according to Research Diagnostic Criteria (RDC)/TMD Axis I diagnosis. Radioimmunoassay was used for the detection of serum 17 beta-oestradiol and progesterone levels in all 142 subjects. The mean progesterone level was significantly higher in control group (11.6 +/- 10.4 ng mL(-1)) compared to women with TMD (8.4 +/- 6.8 ng mL(-1), P = 0.03). No significant difference was found in two groups regarding 17 beta-oestradiol level. Lower progesterone level in women with TMD can suggest the more important role of this hormone in the development of the disorder.
- 出版日期2013-8