Phytochemical evaluation of major bioactive compounds in different cytotypes of five species of Rumex L.

作者：Jeelani Syed Mudassir^*; Farooq Umer; Gupta Ajai Prakash; Lattoo Surrinder K^*

来源：Industrial Crops and Products, 2017, 109: 897-904.

DOI：10.1016/j.indcrop.2017.09.015

• Rumex
• Cytotypes
• LC-MS
• Meiosis
• Polyploidy
• Phytoconstituents

The species of genus Rumex represent a reservoir of important phytoconstituents reputed for their pharmacological activities. In the present study, identification and quantification of major bioactive compounds in five species of Rumex based on tissue- and location-specific comparison among extant cytotypes has been carried out for the first time. Detailed cytological investigations of their populations from NW Himalayas revealed occurrence of different chromosomal races in R. crispus (n = 30, 40), R. dentatus (n = 20, 60) and R. nepalensis (n = 30, 40, 50, 60). Out of ten identified cytotypes, two were identified as novel polyploid types with chromosome counts of 80 and 120 (n = 40 in R. crispus and n = 60 in R. dentatus) respectively. The tissue-specific c.hemo-profiling revealed relative dominance of different phytoconstituents in root followed by leaf and stem respectively. Concentration of phytoconstituents (emodin, physcion, piceatannol, resveratrol and rutin) as determined by LC-MS showed positive correlation with the increasing ploidy status and altitudinal gradients. These results indicate that the species/cytotypes thriving at higher altitudes tend to accumulate copious amounts of secondary metabolites. Chromosomal plasticity in terms of polyploidy seems to enhance the adaptability range of a species particularly at higher altitudes. Further, the genus Rumex appears to be rich repository of desirable bioactive metabolites with robust cytotypic and chemical diversity for its exploitation to develop cultivars of commerce for trade and industry.

• 出版日期2017-12-15