A Facile Synthesis of New 4-Amino-2-iminothiazoles from Unsymmetrical Thioureas

作者:Murthy Yellajyosula Lakshmi Narasimha*; Saviri Rama Mohana Rao; Ramaiah Parimi Atchuta; Nareesh Saranapu
来源:Chemistry Letters, 2012, 41(5): 535-537.
DOI:10.1246/cl.2012.535

摘要

An efficient methodology for the synthesis of 4-amino-2-iminothiazole derivatives has been developed. The synthesis involves the cyclization of unsymmetrical 1-aroyl-3-arylthioureas with a variety of 2-bromo-2-phenylacetonitriles bearing alpha-H in the presence of triethylamine and acetonitrile.

  • 出版日期2012-5-5