A randomized trial of a prenatal genetic testing interactive computerized information aid

作者：Yee Lynn M^*; Wolf Michael; Mullen Rebecca; Bergeron Ashley R; Bailey Stacy Cooper; Levine Robert; Grobman William A

来源：Prenatal Diagnosis, 2014, 34(6): 552-557.

DOI：10.1002/pd.4347

ObjectiveThe aim of this study was to determine whether an interactive computer program could improve patient knowledge regarding genetic screening and diagnostic concepts. MethodsIn this randomized trial, women 6-26weeks' gestation were assigned to standard care with provider-based counseling or to augmented counseling with an interactive computer program. The computer-based tool conveyed information about genetic testing options. Women were administered a 23-item test of content knowledge immediately and 2-4weeks after exposure. Test scores were compared between groups at both points using T-tests. ResultsA total of 150 women were randomized equally between groups. Groups were similar with regard to demographic characteristics. Women randomized to the interactive tool correctly answered a significantly greater proportion of questions than those who received standard counseling (69.4%+/- 14.2% vs. 46.0%+/- 15.2%, p<0.001) on the immediate questionnaire. One hundred and twenty-three (82%) participants participated in the follow-up test. Women randomized to the tool continued to correctly answer a significantly greater proportion of questions (60.6%+/- 16% vs. 49.7%+/- 18.9%, p=0.001). Education, health literacy, electronic health literacy, and other discussions with providers were not associated with a differential benefit from the educational intervention. ConclusionA patient-directed interactive computer program may help providers to convey relevant information about genetic screening and diagnostic concepts.

• 出版日期2014-6
• 单位西北大学