A multipathway coupled domino strategy: I-2-mediated oxidative thionation for direct synthesis of thiobenzamides from miscellaneous substrates

作者：Li, Hong-Zheng; Xue, Wei-Jian; Yin, Guo-Dong^*; Wu, An-Xin

来源：Tetrahedron Letters, 2015, 56(43): 5843-5846.

DOI：10.1016/j.tetlet.2015.08.060

• Multipathway coupled domino reactions
• Imines
• Iodine
• Thiobenzamides

An efficient iodine-mediated multipathway coupled domino reaction has been developed for the synthesis of thiobenzamides from benzylamines, benzylamines/aldehydes, and N-alkyl benzylamines under the same reaction conditions. This approach combines two consecutive domino processes in one pot using iodine as the oxidant.

• 出版日期2015-10-21
• 单位湖北师范大学; 华中师范大学