A Simple Discriminating p-tert-Butylcalix[4]arene Thiospirolactam Rhodamine B Based Colorimetric and Fluorescence Sensor for Mercury Ion and Live Cell Imaging Applications

作者：Anandababu Ambigapathi; Anandan Sambandam; Ashokkumar Muthupandian

来源：ChemistrySelect, 2018, 3(16): 4413-4420.

DOI：10.1002/slct.201800044

<jats:title>Abstract</jats:title><jats:p>The inherent amphiphilic property of modified p‐tert‐butylcalix[4]arene thiospirolactam rhodamine b based ligand for effective colorimetric Off‐On sensor for Hg<jats:sup>2+</jats:sup> ion in neutral aqueous condition, has been investigated by electronic spectroscopic techniques. This ligand discriminates chronic poisonous Hg<jats:sup>2+</jats:sup> ion over various alkali, alkaline earth and transition metal ions due to the presence of thiospirocyclic moiety. The ligand shows an association constant of 3.63 X 10<jats:sup>5</jats:sup> M<jats:sup>‐1</jats:sup> and a detection limit 9.65 X 10<jats:sup>‐9</jats:sup> M for Hg<jats:sup>2+</jats:sup> ion. This ligand is also capable of penetrating into HeLa cell, which could be used to detect Hg<jats:sup>2+</jats:sup> ions in biological system using a fluorescence imaging technique.</jats:p>

• 出版日期2018-4-30