摘要

We present here the synthesis and the transmembrane transport properties of a cholic acid-functionalized pseudorotaxane thread. The anion transport properties of this amphiphilic thread can be changed by the assembly of a [2]-pseudorotaxane. Besides its interest and potential application as chloride transmembrane transporter, the amphiphilic properties of the umbrella thread presented here may be of interest to transport cyclic drugs across the cell membrane.

  • 出版日期2011-10