科研之友
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摘要
A water-soluble fluorescent probe for Hg2+ based on a rhodamine B derivative was designed and synthesized. The new probe showed reversible colorimetric and fluorescent response to Hg2+ in a fully aqueous solution. The probe exhibited real-time detection of Hg2+ with high selectivity in media containing less than 1% organic cosolvent. Furthermore, bioimaging studies indicated that the new probe was cell permeable and suitable for the real-time imaging of Hg2+ in living cells by confocal microscopy.
