Application of 99mTc-DTPA Radiotracer in Persian Cat's Renal Scintigraphy

作者：Assadnassab Gholamreza^*; Oskoei Shahram Dabiri

来源：Tropical Journal of Pharmaceutical Research, 2015, 14(9): 1691-1694.

DOI：10.4314/tjpr.v14i9.21

• Kidney
• Persian cat
• Radiotracer
• Scintigraphy
• Technetium-99m diethylene triamine pentacaetic acid (Tc-99m-DTPA)

Purpose: To evaluate the suitability of Tc-99m-DTPA as a radiotracer in Persian cat's renal scintigraphy.
Methods: twelve adult healthy Persian cats were selected. For scintigraphy, the animals were anesthetized and (TC)-T-99m-DTPA was injected via the femoral vein as a bolus at a dose of 1.5 mCi. Immediately after intravenous injection of radiotracer, scintigraphic operation was conducted on the renal organ. dministration of the radioisotope and accumulation of radioisotope in the tissues was monitored by specific imaging theemanating
Results: Distinct scintigraphic scans were obtained using (TC)-T-99m-DTPA. Visual comparison of the scans indicates that there was no significant difference in the accumulation of radiotracer. In dynamic scans, symmetric and concurrent distribution of Tc-99m-DTPA in the kidney was observed.
Conclusion: The results show that the radiopharmaceutical Tc-99m-DTPA is suitable for use in Persian cat's renal scintigraphy, and this makes it potentially useful in research and clinical practice.

• 出版日期2015-9