Spanish validation of the Negative Symptom Assessment-16 (NSA-16) in patients with schizophrenia

作者：Garcia Alvarez Leticia^*; Paz Garcia Portilla Maria; Alejandra Saiz Pilar; Fonseca Pedrero Eduardo; Teresa Bobes Bascaran Maria; Gomar Jesus; Muniz Jose; Bobes Julio

来源：Revista de Psiquiatria y Salud Mental, 2018, 11(3): 169-175.

DOI：10.1016/j.rpsm.7018.03.001

• Negative symptoms
• NSA-16
• Psychome properties
• Schizophrenia

Introduction: Negative symptoms are prevalent in schizophrenia and associated with a poorer outcome. Validated newer psychometric instruments could contribute to better assessment and improved treatment of negative symptoms. The Negative Symptom Assessment-16 (NSA-16) has been shown to have strong psychometric properties, but there is a need for validation in nonEnglish languages. This study aimed to examine the psychometric properties of a Spanish version of the NSA-16 (Sp-NSA-16).
Material and method: Observational, cross-sectional validation study in a sample of 123 outpatients with schizophrenia. Assessments: NSA-16, PANSS, HDRS, CGI-SCH and PSP.
Results: The results indicate appropriate psychometric properties, high internal consistency (Cronbach's alpha = 0.86), convergent validity (PANSS negative scale, PANSS Marder Negative Factor and CGI-negative symptoms r values between 0.81 and 0.94) and divergent validity (PANSS positive scale and the HDRS r values between 0.10 and 0.34). In addition, the NSA-16 also exhibited discriminant validity (ROC curve = 0.97, 95% CI = 0.94 to 1.00; 94.3% sensitivity and 83.3% specificity).
Conclusions: The Sp-NSA-16 is reliable and valid for measuring negative symptoms in patients with schizophrenia. This provides Spanish clinicians with a new tool for clinical practice and research. However, it is necessary to provide further information about its inter-rater reliability.

• 出版日期2018-9