Assembly of an unprecedented metal-pipemidic acid complex modifying octamolybdates containing like DNA spiral chain

作者：Zhang Qian Nan; Sha Jing Quan^*; Yan Hong; Yang Qing Shan; Zhang Yu; Li Liang; Wang Dong Wen; Yang Xiao Ning

来源：Solid State Sciences, 2014, 32: 20-25.

DOI：10.1016/j.solidstatesciences.2014.03.013

• Polyoxometalates
• Octamolybdates
• Pipemidic acid
• DNA
• Antitumor activity

By introducing antibacterial drugs pipemidic acid into the octamolybdates, an unprecedented compound, [Zn(PPA)(2)(H2O)](2)center dot[Mo8O26]center dot 3.5H(2)O (1) (PPA = pipemidic acid), has been synthesized and characterized by routine physical methods. Single-crystal X-ray diffraction analysis reveals that the title compound contains the right- and left-double-stranded like DNA helical chains, which are assembled together via sharing the beta-Mo-8 clusters forming the fascinating double intertwined inverted helices. The result of the antitumor activities shows that the title compound possesses higher antitumor activity and selectivity.

• 出版日期2014-6
• 单位佳木斯大学