New antioxidant bibenzyl derivative and isoflavonoid from the Tunisian Salsola tetrandra Folsk

作者：Beyaoui Ahlem; Chaari Atef; Ghouila Hatem; Hamza M'hamed Ali; Ben Jannet Hichem^*

来源：Natural Product Research, 2012, 26(3): 235-242.

DOI：10.1080/14786419.2010.536950

• Salsola tetrandra
• Chenopodiaceae
• bibenzyl
• isoflavonoid
• NMR
• antioxidant

Two new phytochemical compounds, Tetranins A and B, 1-(3,5'-dihydroxy-4'-methoxyphenyl)-2-phenylethanol 1 and 5,2'-dihydroxy-5'-methoxy-6, 7-methylenedioxy-isoflavone 2, were isolated from the EtOAc extract of Salsola tetrandra roots. They exhibited a significant antioxidant effect in 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical and 2,2'-azinobis (3-ethylbenzothiazoline-6-sulphonic acid (ABTS) assays. Their structures were elucidated by extensive spectroscopic methods including 1-D-(H-1 and C-13) and 2-D-NMR experiments (CHcorr, HMBC, H-1-H-1 COSY and NOESY) as well as high-resolution ES-MS and they were found to be quite active as antioxidants in the DPPH and ABTS assays.

• 出版日期2012