Undifferentiated Sarcoma of the Liver: A Case Study of an Erythropoietin-Secreting Tumor

作者：Lin JoAnn M; Heath Jonathon E; Twaddell William S; Castellani Rudy J^*

来源：International Journal of Surgical Pathology, 2014, 22(6): 555-558.

DOI：10.1177/1066896913503490

• undifferentiated sarcoma
• embryonal sarcoma
• hepatic
• erythropoietin

Undifferentiated embryonal sarcoma of the liver (UESL) is an uncommon hepatic tumor usually found in children, with rare cases reported in adults. We present a case of a 53-year-old woman with an undifferentiated sarcoma of the liver (USL), which resembles UESL, who initially presented with a markedly elevated hematocrit (61.2%). Cytogenetic studies for polycythemia vera were negative, but the patient%26apos;s erythropoietin (EPO) was elevated. A computed tomography scan and subsequent partial hepatectomy revealed a well-circumscribed, partially cystic mass in the right lobe of the liver measuring 34 cm. Following surgery, the patient%26apos;s EPO level and hematocrit dropped to within normal range and remained so for 1 year, at which point it rose again. A subsequent magnetic resonance imaging scan showed a liver mass at the previous resection margin, consistent with a recurrence. In this case study, we describe the first reported USL resembling an UESL that secretes EPO, which was a useful marker of tumor recurrence.

• 出版日期2014-9