Nuclear Topology, Epigenetics, and Keratinocyte Differentiation

作者:Hughes Michael W*; Lu Wange; Chuong Cheng Ming
来源:Journal of Investigative Dermatology, 2013, 133(9): 2130-2133.
DOI:10.1038/jid.2013.261

摘要

Recent progress in epigenetics reveals dynamic chromatin interactions in the nucleus during development, regeneration, reprogramming, and in disease. Higher-order chromatin organization is manifested as changes in the topological distribution of eu-/heterochromatin and in nuclear morphology. We are now able to gain new knowledge about these changes at the genomic level.

  • 出版日期2013-9

全文