Nighttime procedures are not associated with adverse outcomes in kidney transplantation

作者：Kienzl Wagner Katrin; Schneiderbauer Stefanie; Boesmueller Claudia; Schneeberger Stefan; Pratschke Johann^*; Oellinger Robert

来源：Transplant International, 2013, 26(9): 879-885.

DOI：10.1111/tri.12125

• cold ischemia time
• kidney transplantation
• nighttime
• sleep deprivation
• surgery

Surgeries performed during the night are associated with higher complication rates. The aim of this study was to determine the impact of nighttime surgery on the outcome after kidney transplantation. In all, 873 deceased donor kidney transplants were retrospectively analyzed and grouped according to the time of surgery: daytime (8am to 8pm, n=610) versus nighttime (8pm to 8am, n=263). Statistical analysis compared patient/graft survival, rate of delayed graft DGF), acute rejection rate, and surgical complications. One and 5-year patient and graft survival did not differ between daytime and nighttime transplants. DGF occurred in 31.1% of daytime compared to 37.6% of nighttime procedures (P=0.06). Acute allograft rejection was observed in 22.6% of daytime compared to 18.3% in nighttime graft recipients (P=0.15). Nighttime procedures were associated with 22.4% complications compared to 22.1% in daytime procedures (P=0.92). Most importantly, if transplantations were postponed until the next morning, cold ischemia time (CIT) would have increased from 16.6h to 24.6h (P%26lt;0.0001) which would have resulted in decreased long-term survival (P%26lt;0.02). Nighttime kidney transplants are neither associated with a higher surgical complication rate nor worse 5-year outcomes than daytime procedures, thus are justified to keep CIT short.

• 出版日期2013-9