An efficient, transition-metal-free process for the synthesis of substituted dihydrofurans via a Michael/cyclization tandem reaction

作者：Wu, Ming-Yu; Wang, Ming-Qi; Li, Kun^*; Feng, Xing-Wen; He, Ting; Wang, Na; Yu, Xiao-Qi

来源：Tetrahedron Letters, 2011, 52(6): 679-683.

DOI：10.1016/j.tetlet.2010.11.151

• Dihydrofuran
• Tandem reaction
• Nitrostyrene
• 1,3-Dicarbonyl compounds

An efficient green route for the synthesis of substituted dihydrofurans was developed through a simple base-catalyzed, tandem reaction of nitrostyrene with 1,3-dicarbonyl compounds. The desired products were prepared with a large substrate scope and in excellent yields (up to 95%).

• 出版日期2011-2-9
• 单位四川大学