科研之友
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摘要
Background: To evaluate the results of macular hole surgery using pars plana vitrectomy with internal limiting membrane peeling and intravitreal tamponade (air, gas, or a combination of air with gas) in a series of consecutive patients.
Design: A retrospective, monocentric case series.
Patients and methods: Eighty-six consecutive patients with a full thickness macular hole, who underwent a pars plana vitrectomy with internal-limiting membrane peeling, were included in the case series. The stage of the macular hole, the pre- and postsurgical best corrected visual acuity, the closure rate, peri - and postsurgical complications were obtained from the original patient files.
Results: All patients had a postoperative follow-up of 6 months or more. All 68 eyes had a full thickness macular hole. The mean age was 70 years, 63 % were women and 37 % men. Fifty-seven of the 68 macular holes (84 %) were closed postsurgically.
The mean initial visual acuity was 0.20. After both 6 and 12 months a statistically significant improvement of visual acuity was shown with a mean improvement of 0.38 after 6 months and 0.41 after 12 months. Thirty-three eyes (49 %) had an initial visual acuity of less than 0.2 and 18 of the 68 eyes (26 %) of less than 0.1. Yet, the patients who had an initial visual acuity of more than 0.1 had a statistically significant (p > 0.000) visual improvement after 6 months compared to those who had an initial visual acuity of less than 0.1. After 12 months there was no difference among the two groups (p > 0.678). Except for reversible hypotonies after 23 g vitrectomy no severe peri-or postoperative complications occurred.
Conclusions: Macular hole surgery with vitrectomy, peeling of the internal limiting membrane and air/gas tamponade led to good anatomical and visual results with a low rate of peri-and postoperative complications.
- 出版日期2011-11
