An Official American Thoracic Society Clinical Practice Guideline: Exercise-induced Bronchoconstriction

作者：Parsons, Jonathan P.; Hallstrand, Teal S.; Mastronarde, John G.; Kaminsky, David A.; Rundell, Kenneth W.; Hull, James H.; Storms, William W.; Weiler, John M.; Cheek, Fern M.; Wilson, Kevin C.; Anderson, Sandra D.

来源：American Journal of Respiratory and Critical Care Medicine, 2013, 187(9): 1016-1027.

DOI：10.1164/rccm.201303-0437ST

• EUCAPNIC VOLUNTARY HYPERVENTILATION
• FISH-OIL SUPPLEMENTATION
• CROSS-COUNTRY SKIERS
• ACTING BETA-AGONISTS
• JOINT TASK-FORCE
• INDUCED ASTHMA
• INDUCED BRONCHOSPASM
• AIRWAY HYPERRESPONSIVENESS
• CHALLENGE TESTS
• EUROPEAN-ACADEMY

Background: Exercise-induced bronchoconstriction (EIB) describes acute airway narrowing that occurs as a result of exercise. EIB occurs in a substantial proportion of patients with asthma, but may also occur in individuals without known asthma. @@@ Methods: To provide clinicians with practical guidance, a multidisciplinary panel of stakeholders was convened to review the pathogenesis of FIB and to develop evidence-based guidelines for the diagnosis and treatment of FIB. The evidence was appraised and recommendations were formulated using the Grading of Recommendations, Assessment, Development, and Evaluation approach. @@@ Results: Recommendations for the treatment of EIB were developed. The quality of evidence supporting the recommendations was variable, ranging from low to high. A strong recommendation was made for using a short-acting beta(2)-agonist before exercise in all patients with EIB. For patients who continue to have symptoms of EIB despite the administration of a short-acting beta(2)-agonist before exercise, strong recommendations were made for a daily inhaled corticosteroid, a daily leukotriene receptor antagonist, or a mast cell stabilizing agent before exercise. @@@ Conclusions: The recommendations in this Guideline reflect the currently available evidence. New clinical research data will necessitate a revision and update in the future.

• 出版日期2013-5-1