摘要

In mouse parotid glands, we found expression of skeletal muscle actin (actin-alpha 1) protein and mRNA. We isolated myoepithelial cells from the mouse parotid glands and investigated their actin-alpha 1 expression because smooth muscle actin (actin-alpha 2) has been used as a marker for myoepithelial cells. We used actin-alpha 1 expression to identify pathological changes in diabetic non-obese diabetic (NOD; NOD/ShiJcl) mice-a mouse model for Sjogren's syndrome-and found myoepithelial cells to be decreased or atrophied in the diabetic state.

  • 出版日期2013