Photoreactions with a Twist: Atropisomerism-Driven Divergent Reactivity of Enones with UV and Visible Light

作者：Vallavoju Nandini; Sreenithya Avadakkam; Ayitou Anoklase J L; Jockusch Steffen; Sunoj Raghavan B^*; Sivaguru Jayaraman^*

来源：Chemistry - A European Journal, 2016, 22(32): 11339-11348.

DOI：10.1002/chem.201601509

• asymmetric photochemistry
• atropisomerism
• atropselective photoreactions
• enones
• hydrogen abstraction
• photochirogenesis

Light-induced transformation of atropisomeric and achiral enones displays divergent reactivity. Photocyclization leading to 3,4-dihydroquinolin-2-one was observed with achiral enone carboxamide, whereas the atropisomeric enone carboxamides underwent hydrogen abstraction leading to spiro-beta-lactams. Detailed photochemical, photophysical, and theoretical investigations have provided insight into this divergent reactivity and selectivity.

• 出版日期2016-8-1