Detection and management of non-motor symptoms in Parkinson's disease: impact on their prevalence

作者：Rodriguez Violante Mayela^*; Cervantes Arriaga Amin

来源：Revista Medica de Chile, 2011, 139(8): 1032-1038.

• Movement disorders
• Parkinson disease
• Questionnaires

Background: Non-motor symptoms are common among patients with Parkinson disease and include cognitive, psychiatric, sleep and autonomic dysfunctions. Aim: To determine if the detection of non-motor symptoms along with the appropriate referral to an specialist has an impact on their prevalence after one year follow-up. Material and Methods: We included 60 patients diagnosed with Parkinson's disease attending to the Movement Disorder Clinic. The presence of non-motor symptoms was determined by the non-motor symptom questionnaire (NMSQuest). Results: The mean NMSQuest scores at baseline and at one year follow up were 12.6 +/- 6.2 and 9.9 +/- 5.6, respectively (p < 0.01). The non-motor symptoms that showed a statistically significant differences in frequency between baseline and the final assessment were constipation (p = 0.04), urinary urgency (p = 0.02), hallucinations (p = 0.04), dizziness (p = 0.02) and vivid dreams (p = 0.04). Conclusions: Intentional search for non-motor symptoms in patients with Parkinson's disease along with a multidisciplinary approach has an impact on their prevalence. The change in specific symptoms is probably related to adjustments in dopaminergic management. (Rev Med Chile 2011; 139: 1032-1038).

• 出版日期2011-8