Discordance between ICD-Coded Myocardial Infarction and Diagnosis according to the Universal Definition of Myocardial Infarction

作者：Diaz Garzon Jorge; Sandoval Yader; Smith Stephen W; Love Sara; Schulz Karen; Thordsen Sarah E; Johnson Benjamin K; Driver Brian; Jacoby Katherine; Carlson Michelle D; Dodd Kenneth W; Moore Johanna; Scott Nathaniel L; Bruen Charles A; Hatch Ryan; Apple Fred S^*

来源：Clinical Chemistry, 2017, 63(1): 415-419.

DOI：10.1373/clinchem.2016.263764

BACKGROUND: International Classification of Diseases (ICD) coding is the standard diagnostic tool for healthcare management. At present, type 2 myocardial infarction (T2MI) classification by the Universal Definition of Myocardial Infarction (MI) remains ignored in the ICD system. We determined the concordance for the diagnosis of MI using ICD-9 coding vs the Universal Definition.
METHODS: Cardiac troponin I(cTnI) was measured by both contemporary (cTnI) and high-sensitivity (hsc-TnI) assays in 1927 consecutive emergency department (ED) patients [Use of TROPonin In Acute coronary syndromes (UTROPIA) cohort] who had cTnI ordered on clinical indication. All patients were adjudicated using both contemporary and hs-cTnI assays. The Kappa index and McNemar test were used to assess concordance _between ICD-9 code 410 and type 1 MI (T1MI) and type 2 MI (T2MI).
RESULTS: Among the 249 adjudicated MIs using the contemporary cTnI, only 69 (28%) were ICD-coded MIs. Of 180 patients not ICD coded as MI, 34 (19%) were T1MI and 146 (81%) were T2MI. For the ICD-coded MIs, 79% were T1MI and 21% were T2MI. A fair Kappa index, 0.386, and a McNemar difference of 0.0892 (P < 0.001) were found. Among the 207 adjudicated MIs using the hs-cTnI assay, 67 (32%) were ICD coded as MI. Of the 140 patients not ICD coded as MI, 27 (19%) were T1MI and 113 (81%) were T2MI. For the ICD-coded MIs, 85% were T1MI and 15% T2MI. A moderate Kappa index, 0.439, and a McNemar difference of 0.0674 (P < 0.001) were found.
CONCLUSIONS: ICD-9 coded MIs captured only a small proportion of adjudicated MIs, primarily from not coding T2MI. Our findings emphasize the need for an ICD code for T2MI.

• 出版日期2017-1