Development of a disposable kit with fully automatic self-shielding reactor for [F-18]FDG synthesis

作者：Oh Seyoung; Nam Kyungrok; Lee Kyo Chul; Ghergherehchi Mitra; Kim Byungil; Kim Jung Young; Song Ho Seung; Chai Jong Seo^*

来源：Applied Radiation and Isotopes, 2018, 131: 23-29.

DOI：10.1016/j.apradiso.2017.10.044

• 2-[F-18]fluoro-2-deoxy-D-glucose [F-18]FDG
• Radiopharmaceuticals
• Self-shielding reactor
• Automated synthesis system

A self-shielding device for the synthesis of radiopharmaceuticals was developed and fabricated in this study. Radiation exposure was minimized by the self-shielding of the kit, installation of the disposable kit in the auxiliary chamber while in a shielded state, and discharge of the kit into a radioactive waste container upon completion of the synthesis process. The developed self-shielding synthesis kit was tested by synthesizing 2-[F-18] fluoro-2-deoxy-D-glucose ([F-18]FDG) in order to verify its performance.

• 出版日期2018-1