Nanostructure Changes in the Intervertebral Discs after Experimental Laser Irradiation

作者：Byval'tsev V A^*; Panasenkov S Yu; Belykh E G; Ivanov N A; Tsyganov P Yu; Nikiforov S B; Sorokovikov V A; Grigor'ev E G; Kolesnikov S I

来源：Bulletin of Experimental Biology and Medicine, 2015, 158(4): 504-507.

DOI：10.1007/s10517-015-2795-y

• intervertebral discs
• atomic force microscopy
• nanostructural changes
• bioengineering
• laser

Laser-induced changes in the intervertebral discs were studied by the method of atomic force microscopy. Alteration of the proximal caudal intervertebral discs was modeled in rats: puncture and exposure to diode laser (2, 3, or 5 W) in constant or pulse regimens or only puncture (control). Nanostructure of disc surface was estimated by surface skewness, root mean square and average roughness, and coefficient of kurtosis. Maximum positive effect and signs of regenerative changes in the surface microstructure of the intervertebral discs were found after exposure to laser (2-3 W) in constant or pulse regimens.

• 出版日期2015-2