科研之友
微信
新浪微博
Facebook
分享链接
摘要
The morphology and the stability of supported phospholipid (DPPC, DMPC, DOPC) layers prepared by solution spreading on mica were investigated by atomic force microscopy. The samples were analyzed ex-situ just after solvent evaporation and after a hydration step, and in-situ with immersion in a buffer solution. Film morphology depended on the type of phospholipid and on the hydration level of the sample. For DPPC, in particular, morphology evolved from non-uniform deposits through multilayer structures to a final pattern with large bilayer terraces, as the sample was hydrated and then immersed in the liquid cell. The film morphology was stable for all the systems investigated, thus indicating that cast films are suitable for studying time-dependent biological and physical phenomena.
- 出版日期2004-4
