科研之友
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摘要
Synaptic plasticity is known to be intrinsically linked to cytoskeletal remodelling. In a new study published in this issue of The EMBO Journal, Rust et al have therefore generated and analysed a forebrain-specific mouse knockout of the actin-severing factor n-cofilin. Intriguingly, these mice exhibit a particular form of learning impairment-intact working memory but impaired spatial reference memory, correlating with a deficit in long-lasting long-term potentiation (LTP).
- 出版日期2010-6-2
- 单位河北医科大学
