Novel Feline Leukemia Virus Interference Group Based on the env Gene

作者:Miyake Ariko; Watanabe Shinya; Hiratsuka Takahiro; Ito Jumpei; Minh Ha Ngo; Makundi Isaac; Kawasaki Junna; Endo Yasuyuki; Tsujimoto Hajime; Nishigaki Kazuo*
来源:Journal of Virology, 2016, 90(9): 4832-4837.
DOI:10.1128/JVI.03229-15

摘要

Feline leukemia virus (FeLV) subgroups have emerged in infected cats via the mutation or recombination of the env gene of subgroup A FeLV (FeLV-A), the primary virus. We report the isolation and characterization of a novel env gene, TG35-2, and report that the TG35-2 pseudotype can be categorized as a novel FeLV subgroup. The TG35-2 envelope protein displays strong sequence identity to FeLV-A Env, suggesting that selection pressure in cats causes novel FeLV subgroups to emerge.

  • 出版日期2016-5