Postoperative Quality of Life: Development and Validation of the "Dysfunction after Upper Gastrointestinal Surgery" Scoring System

作者：Nakamura Misuzu; Hosoya Yoshinori; Umeshita Koji; Yano Masahiko; Doki Yuichiro; Miyashiro Isao; Dannoue Hideo; Mori Masaki; Kishi Kentaro; Lefor Alan T^*

来源：Journal of the American College of Surgeons, 2011, 213(4): 508-514.

DOI：10.1016/j.jamcollsurg.2011.07.007

BACKGROUND: Although postoperative quality of life is an important outcomes measure, few tools exist to evaluate patients specifically after upper gastrointestinal surgery. The previously developed Dysfunction After Upper Gastrointestinal Surgery (DAUGS) 32 scoring system has been further refined to include just 20 items. This study was undertaken to validate the refined evaluation tool.
STUDY DESIGN: The study was performed as a survey, administered to patients after upper gastrointestinal resection at 3 separate institutions.
RESULTS: The DAUGS20 score after gastrectomy (n = 662) was 27.8 and that after esophagectomy (n = 221) was 36.1, showing a significant difference (p < 0.05). The score after distal gastrectomy (n = 282) was 25.4 and that after total gastrectomy (n = 149) was 32.0, showing a significant (p < 0.05) difference. The alpha coefficient of all items on the DAUGS20 system was 0.904 and Cronbach's alpha coefficients of the subscales were 0.612 to 0.856, demonstrating high reliability of this evaluation tool. In addition, 7 factors were extracted from the 20 items using definitive factor analysis, to verify validity.
CONCLUSIONS: Patient quality of life should be evaluated as an outcomes measure after surgical resection for cancer, just as overall survival is analyzed. The DAUGS20 score is reliable, has validity in the evaluation of postoperative patients, and is a valuable tool to assess patient quality of life after upper gastrointestinal surgery for cancer. (J Am Coll Surg 2011;213:508-514.

• 出版日期2011-10