A panel of peralkylated sulfur-guanidine type bases: Novel pro-ligands for use in biomimetic coordination chemistry

作者：Neuba Adam; Rohrmueller Martin; Hoelscher Rebecca; Schmidt Wolf Gero^*; Henkel Gerald

来源：Inorganica Chimica Acta, 2015, 430: 225-238.

DOI：10.1016/j.ica.2015.03.015

• Nitrogen-sulfur donor ligands
• Guanidine ligands
• Thiolate ligands
• Cu-A donor set ligands
• DFT

A series of novel hybrid molecules containing sulfur and nitrogen donor functions simultaneously has been synthesized and characterized. Designed for use in biomimetic coordination chemistry, these molecules are expected to act directly or in specific precursor roles as polyfunctional Lewis bases towards metal-based Lewis acids to form complexes with biological relevance. Their principal architecture is based on aliphatic or aromatic backbones connecting guanidine moieties with sulfur-containing thioether or disulfide portions. Based on acyclic tetramethylguanidino units and their cyclic dimethylethyl-substituted counterparts, a panel of forty-six members of this class of compounds are presented here. The associated denticity extends from bidentate (N/S donor sets) and tridentate (N/N/S donor sets) via tetradentate (N/N/S/S donor sets) to pentadentate (N/N/N/S/S donor sets). Five of these novel systems were structurally characterized and subjected to geometry optimizations using density-functional theory (DFT).

• 出版日期2015-5-1