Adipose tissue-derived stem cells secrete CXCL5 cytokine with chemoattractant and angiogenic properties

作者：Zhang Haiyang; Ning Hongxiu; Banie Lia; Wang Guifang; Lin Guiting; Lue Tom F; Lin Ching Shwun^*

来源：Biochemical and Biophysical Research Communications, 2010, 402(3): 560-564.

DOI：10.1016/j.bbrc.2010.10.090

• Adipose tissue-derived stem cells
• CXCL5
• CXCR2
• Chemoattractant
• Angiogenic

Adipose tissue-derived stem cells (ADSC) secreted CXCL5 cytokine abundantly and higher passaged ADSC up to passage 6 (P6) secreted more CXCL5 than lower passaged ADSC Higher passaged ADSC also appeared to express higher levels of CXCL5 receptor, i e, CXCR2 Both CXCL5 and CXCR2 were localized in the tunica intima and tunica adventitia of blood vessels in adipose tissue Colocalization with CD34 further indicates their association with the putative ADSC in tunica adventitia Migration as

• 出版日期2010-11-19
• 单位山东大学